A new bio-ink have been developed by the group of researchers from Korea Institute of Science and Technology (KIST) which is biocompatible and biodegradable in nature. This bio-ink can be used for the development of artificial bio-organs by using 3D bioprinting technology which can be a hot cake for future space technology and research industry. 3D bioprinting technology has potential to enhance the experience in medical education, training and research in future. Probably, this technology will replace the animal testing models in medical science research.
3D bioprinting and related issues
3D bioprinter prints the artificial bio-organs using bio-ink but the main problem is the curing of the printed bio-organs. Because the curing is done by two methods, one is chemical cross linking and another one is UV light curing. And both the methods are harmful. During UV curing of artificial organs, UV light damages the cells’ DNA and causes cytotoxicity. In cross linking curing method, chemical reagents are being used which also may cause the cytotoxicity and damage of cells.
Newly developed bio-ink
Newly developed bio-ink is having bio-organic compound named poly(organophosphazene). This compound makes temperature sensitive hydrogel and it exist as liquid at lower temperature. While at body temperature, this hydrogel form very strong and stable structure. Therefore, it is very compatible and can be used in bio-ink for 3D bioprinting of artificial organism and tissue regeneration.